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Article

Functional groups required for the stability of yeast RNA triphosphatase in vitro and in vivo.

The Journal of biological chemistry - 10 Aug 2001

Bisaillon M, Shuman S

Abstract excerpt

Cet1, the RNA triphosphatase component of the yeast mRNA capping apparatus, catalyzes metal-dependent gamma-phosphate hydrolysis within the hydrophilic interior of an eight-strand beta barrel (the "triphosphate tunnel"), which rests upon a globular protein core (the "pedestal"). We performed a structure-guided alanine scan of 17 residues located in the tunnel (Ser(373), Thr(375), Gln(405), His(411), Ser(429),...

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Identifiers

PMID: 11395522
DOI: 10.1074/jbc.M104936200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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