Article
COMT genotypes and use of antipsychotic medication: linking population-based prescription database to the HUNT study.
Pharmacoepidemiology and drug safety - 1 Apr 2008
Hagen Knut, Stovner Lars Jacob, Skorpen Frank, Pettersen Elin, Zwart John-Anker
Abstract excerpt
PURPOSE: The aim of this prospective study was to evaluate the impact of codon 158 polymorphism at the catechol-O-methyltransferase (COMT) gene on prescription of antipsychotic medication in a general population. METHODS: The sample comprised 2623 non-diabetic individuals who participated in the Nord-Trøndelag Health Study (HUNT) in the period 1995-97 and who were alive 1 January 2004. The subjects were followed...
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