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Article

The impact of the catechol-O-methyltransferase Val158Met polymorphism on survival in the general population--the HUNT study.

BMC medical genetics - 19 Jun 2007

Hagen Knut, Stovner Lars J, Skorpen Frank, Pettersen Elin, Zwart John-Anker

Abstract excerpt

BACKGROUND: The catechol-O-methyltransferase (COMT) gene contains a functional polymorphism, Val158Met which has been related to common diseases like cancer, psychiatric illness and myocardial infarction. Whether the Val158Met polymorphism is associated with survival has not been evaluated in the...

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Identifiers

PMID: 17577421
DOI: 10.1186/1471-2350-8-34
PMCID: PMC1906749

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17577421-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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The impact of the catechol-O-methyltransferase Val158Met polymorphism on survival in the general population--the HUNT study.PMID 17577421Read ↗

High systolic blood pressure is associated with Val/Val genotype in the catechol-o-methyltransferase gene. The Nord-Trøndelag Health Study (HUNT).Semantic proximity Read ↗

Association of Catechol-O-methyltransferase (COMT Val158Met) with future risk of cardiovascular disease in depressed individuals - a Swedish population-based cohort study.Semantic proximity Read ↗

Potential Impact of COMT-rs4680 G > A Gene Polymorphism in Coronary Artery DiseaseSemantic proximity Read ↗

Association between the low activity genotype of catechol-O-methyltransferase and myocardial infarction in a hypertensive population.Semantic proximity Read ↗

Functional COMT Val158Met polymorphism, risk of acute coronary events and serum homocysteine: the Kuopio ischaemic heart disease risk factor study.Semantic proximity Read ↗

Depression and anxiety in relation to catechol-O-methyltransferase Val158Met genotype in the general population: the Nord-Trøndelag Health Study (HUNT).Semantic proximity Read ↗

Impact of Catechol-O-Methyltransferase Val 158Met (rs4680) Polymorphism on Breast Cancer Susceptibility in Asian PopulationSemantic proximity Read ↗

The association between headache and Val158Met polymorphism in the catechol-O-methyltransferase gene: the HUNT Study.Semantic proximity Read ↗

Catechol O-methyltransferase val158-met polymorphism is associated with abdominal obesity and blood pressure in men.Semantic proximity Read ↗

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Effect of COMT Val158Met Polymorphism on Stroke Functional Outcome and Recovery.Semantic proximity Read ↗

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