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Article

Urinary cortisol to cortisone metabolites ratio in prednisone-treated and spontaneously hypertensive patients.

Journal of hypertension - 1 Mar 2008

Olivieri Oliviero, Pizzolo Francesca, Ravagnani Viviana, Moretti Lorenzo, Carletto Antonio, Faccini Giovanni, Pasini Francesco, Friso Simonetta, Corrocher Roberto

Abstract excerpt

OBJECTIVE AND METHODS: Prednisone and its active metabolite prednisolone, both substrates for 11beta-hydroxysteroid dehydrogenase type 2 (11beta-HSD2), may represent a pharmacological challenge for the enzyme. The aim of the present work was to define the possible role of abnormal cortisol/cortisone handling, as revealed by an urinary tetrahydrocortisol + allotetrahydrocortisol (THFs)/tetrahydrocortisone (THE)...

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Identifiers

PMID: 18300859
DOI: 10.1097/HJH.0b013e3282f2d35e

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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