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Article

Antigen Presenting Cells Contribute to Persistent Immune Activation Despite Antiretroviral Therapy Initiation During Hyperacute HIV-1 Infection.

Frontiers in immunology - 1 Jan 2021

Naidoo Kewreshini K, Ndumnego Okechukwu C, Ismail Nasreen, Dong Krista L, Ndung'u Thumbi

Abstract excerpt

Human immunodeficiency virus (HIV)-induced changes in immune cells during the acute phase of infection can cause irreversible immunological damage and predict the rate of disease progression. Antiretroviral therapy (ART) remains the most effective strategy for successful immune restoration in immunocompromised people living with HIV and the earlier ART is initiated after infection, the better the long-term...

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Identifiers

PMID: 34630420
DOI: 10.3389/fimmu.2021.738743
PMCID: PMC8498034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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