Article
HIV-1 matrix protein p17 induces human plasmacytoid dendritic cells to acquire a migratory immature cell phenotype.
Proceedings of the National Academy of Sciences of the United States of America - 11 Mar 2008
Fiorentini Simona, Riboldi Elena, Facchetti Fabio, Avolio Manuela, Fabbri Marco, Tosti Giorgio, Becker Pablo D, Guzman Carlos A, Sozzani Silvano, Caruso Arnaldo
Abstract excerpt
Numerical and functional defects in plasmacytoid dendritic cells (pDCs) are an important hallmark of progressive HIV-1 infection, yet its etiology remains obscure. HIV-1 p17 matrix protein (p17) modulates a variety of cellular responses, and its biological activity depends on the expression of p1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
