Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel polymorphism in human cytosine DNA-methyltransferase-3B promoter is associated with an increased risk of lung cancer.

Cancer research - 1 Sept 2002

Shen Hongbing, Wang Luo, Spitz Margaret R, Hong Waun K, Mao Li, Wei Qingyi

Abstract excerpt

DNA repair is central to genomic integrity. Reduced expression of several nucleotide excision repair genes has been demonstrated to be associated with increased risk of lung cancer. Because methylation of gene promoters is one of the major regulatory mechanisms of gene expression and most nucleot...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to DNA (Cytosine-5-)-Methyltransferases
Share to DNA Methyltransferase 3B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Logistic Models

Share to Lung Neoplasms

Share to Promoter Regions, Genetic

Share to Risk Factors

Share to Smoking

Source

Identifiers

PMID: 12208751

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12208751-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel polymorphism in human cytosine DNA-methyltransferase-3B promoter is associated with an increased risk of lung cancer.PMID 12208751Read ↗

DNMT3B polymorphisms and risk of primary lung cancer.Semantic proximity Read ↗

A novel C/T polymorphism in the core promoter of human de novo cytosine DNA methyltransferase 3B6 is associated with prognosis in head and neck cancer.Semantic proximity Read ↗

The rs1550117 A>G variant in DNMT3A gene promoter significantly increases non-small cell lung cancer susceptibility in a Han Chinese population.Semantic proximity Read ↗

Expression of Delta DNMT3B variants and its association with promoter methylation of p16 and RASSF1A in primary non-small cell lung cancer.Semantic proximity Read ↗

Double-strand break damage and associated DNA repair genes predispose smokers to gene methylation.Semantic proximity Read ↗

Combined effects of cigarette smoking, DNA methyltransferase 3B genetic polymorphism, and DNA damage on lung cancer.Semantic proximity Read ↗

Associations of DNMT3B -149C>T and -2437T>A polymorphisms and lung cancer risk in Chinese population.Semantic proximity Read ↗

The DNMT3B -579G>T Polymorphism Is Significantly Associated With the Risk of Gastric Cancer but not Lung Cancer in Chinese Population.Semantic proximity Read ↗

Methyl-CpG binding domain 1 gene polymorphisms and risk of primary lung cancer.Semantic proximity Read ↗

Association of DNMT3B -283T>C polymorphism with risk of lung and gastric cancer: a case-control study and a meta-analysis.Semantic proximity Read ↗

DNMT3B polymorphisms and cancer risk: a meta analysis of 24 case-control studies.Semantic proximity Read ↗

Polymorphisms of the DNMT3B gene and risk of squamous cell carcinoma of the head and neck: a case-control study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.