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Article

A novel C/T polymorphism in the core promoter of human de novo cytosine DNA methyltransferase 3B6 is associated with prognosis in head and neck cancer.

International journal of oncology - 1 Oct 2004

Wang Luo, Rodriguez Marivonne, Kim Edward S, Xu Yunling, Bekele Neby, El-Naggar Adel K, Hong Waun Ki, Mao Li, Oh Yun W

Abstract excerpt

New biomarkers for head and neck squamous cell carcinoma (HNSCC) patients are being sought to help predict disease outcome, guide treatment, and develop new treatments. In the present study, the association between a novel functional C/T polymorphism in the core promoter of cytosine DNA methyltransferase (DNMT) 3B6 and overall survival of HNSCC patients was investigated. Genomic DNA was extracted from tumor...

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Share to Aged, 80 and over
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA (Cytosine-5-)-Methyltransferases

Share to DNA Methyltransferase 3B

Share to Head and Neck Neoplasms

Share to Polymorphism, Genetic

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Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 15375549

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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