Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel polymorphisms in the SUV39H2 histone methyltransferase and the risk of lung cancer.

Carcinogenesis - 1 Nov 2006

Yoon Kyong-Ah, Hwangbo Bin, Kim Il-Jin, Park Sohee, Kim Hee Sun, Kee Hyun Jung, Lee Jong Eun, Jang Yeun Kyu, Park Jae-Gahb, Lee Jin Soo

Abstract excerpt

Histone H3 lysine 9 (H3-K9) methylation and DNA methylation are important features of mammalian heterochromatin. Suppressor of variegation 3-9 homolog 2 (SUV39H2) is the histone methyltransferase that is required to methylate H3-K9, leading to transcriptional repression or silencing of target genes. In this study, we investigated the association of SUV39H2 polymorphisms and the risk of lung cancer. From the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Silencing

Share to Histone-Lysine N-Methyltransferase

Share to Histone Methyltransferases

Share to Protein Methyltransferases

Share to Smoking

Source

Identifiers

PMID: 16774942
DOI: 10.1093/carcin/bgl084

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel polymorphisms in the SUV39H2 histone methyltransferase and the risk of lung cancer.PMID 16774942Read ↗

SNP rs10248565 in HDAC9 as a novel genomic aberration biomarker of lung adenocarcinoma in non-smoking women.Semantic proximity Read ↗

Polymorphisms of MLH1 and MSH2 genes and the risk of lung cancer among never smokers.Semantic proximity Read ↗

The rs1550117 A>G variant in DNMT3A gene promoter significantly increases non-small cell lung cancer susceptibility in a Han Chinese population.Semantic proximity Read ↗

SUV39H1 Reduction Is Implicated in Abnormal Inflammation in COPDSemantic proximity Read ↗

Integrative analyses of N6-methyladenosine-associated single-nucleotide polymorphisms (m6A-SNPs) identify tumor suppressor gene AK9 in lung cancer.Semantic proximity Read ↗

Genotyping and molecular dynamic simulations reveal the role of MSH2 DNA repair polymorphisms in lung cancer risk.Semantic proximity Read ↗

Associations of DNMT3B -149C>T and -2437T>A polymorphisms and lung cancer risk in Chinese population.Semantic proximity Read ↗

Genetic variant of miR-4293 rs12220909 is associated with susceptibility to non-small cell lung cancer in a Chinese Han population.Semantic proximity Read ↗

The DNMT3B -579G>T Polymorphism Is Significantly Associated With the Risk of Gastric Cancer but not Lung Cancer in Chinese Population.Semantic proximity Read ↗

Neuronal acetylcholine receptor subunit alpha-9 (CHRNA9) polymorphisms are associated with NSCLC risk in a Chinese population.Semantic proximity Read ↗

Impact of GTF2H1 and RAD54L2 polymorphisms on the risk of lung cancer in the Chinese Han population.Semantic proximity Read ↗

The HDAC2-MTA3 interaction induces nonsmall cell lung cancer cell migration and invasion by targeting c-Myc and cyclin D1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.