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Article

The organic solute transporter alpha-beta, Ostalpha-Ostbeta, is essential for intestinal bile acid transport and homeostasis.

Proceedings of the National Academy of Sciences of the United States of America - 11 Mar 2008

Rao Anuradha, Haywood Jamie, Craddock Ann L, Belinsky Martin G, Kruh Gary D, Dawson Paul A

Abstract excerpt

The apical sodium-dependent bile acid transporter (Asbt) is responsible for transport across the intestinal brush border membrane; however, the carrier(s) responsible for basolateral bile acid export into the portal circulation remains to be determined. Although the heteromeric organic solute transporter Ostalpha-Ostbeta exhibits many properties predicted for a candidate intestinal basolateral bile acid...

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Identifiers

PMID: 18292224
DOI: 10.1073/pnas.0712328105
PMCID: PMC2268840

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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