Article
Enteric adenovirus type 40: complementation of the E4 defect in Ad2 dl808.
Virology - 1 Jul 1991
Mautner V, Mackay N
Abstract excerpt
The enteric adenovirus type 40 cannot be passaged in HeLa cells, but will grow productively in cells that express the E1B region of adenovirus types 2 or 5. Even in such permissive cells, the lytic cycle is prolonged, there is an abnormal pattern of E1B early gene expression and a failure to switch off host cell functions, suggesting that other gene functions might be impaired in Ad40. For Ad2, E4 ORF 6 and ORF 3...
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