Article
A protective effect of glutathione-S-transferase GSTP1*Val(105) against polymorphic light eruption.
The Journal of investigative dermatology - 1 Aug 2008
Millard Thomas P, Fryer Anthony A, McGregor Jane M
Abstract excerpt
Polymorphic light eruption (PLE) is a common skin disease, susceptibility to which is genetically determined. The prevalence of PLE is significantly increased in patients with lupus erythematosus (LE) including subacute cutaneous lupus erythematosus (SCLE) and discoid lupus erythematosus (DLE), which may reflect a common genetic background. Experimental evidence supports a role for reactive oxygen species (ROS)...
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