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Article

Polymorphic light eruption and skin cancer prevalence: is one protective against the other?

15 Oct 2008

Abstract excerpt

BACKGROUND: Ultraviolet (UV) radiation (UVR) interacts with chromophores in cutaneous cells with consequent antigenicity. The normal response to this is a downregulation of immune responsiveness. Failure of the immune system to downregulate and to ignore transient photoantigens in human skin results in polymorphic light eruption (PLE), the commonest of the photodermatoses. UVR initiates and promotes skin cancer...

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Identifiers

PMID: 18945307
DOI: 10.1111/j.1365-2133.2008.08734.x

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