Article
Glutathione S-transferase genotype and risk of systemic lupus erythematosus in Koreans.
Lupus - 1 Jan 2005
Kang T Y, El-Sohemy A, Comelis M C, Eny K M, Bae S C
Abstract excerpt
Oxidative stress caused by poor detoxification efficiency of reactive oxygen species (ROS) may play a role in the development of systemic lupus erythematosus (SLE). Glutathione S-transferase (GST) is involved in the detoxification of ROS and genetic polymorphisms of GSTM1, GSTT1 and GSTP1 are associated with altered enzyme activity. The aim of this study was to determine whether GSTMI (deletion), GSTT1 (deletion)...
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