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Article

Analysis of glutathione S-transferase Pi isoform (GSTP1) single-nucleotide polymorphisms and macular telangiectasia type 2.

International ophthalmology - 1 Dec 2010

Szental Joshua A, Baird Paul N, Richardson Andrea J, Islam F M Amirul, Scholl Hendrik P N, Charbel Issa Peter, Holz Frank G, Gillies Mark, Guymer Robyn H

Abstract excerpt

Recent imaging studies have suggested that macular pigment is decreased centrally in macular telangiectasia type 2 (MT2). The uptake of xanthophyll pigment into the macula is thought to be facilitated by a xanthophyll-binding protein (XBP). The Pi isoform of glutathione S-transferase (GSTP1) represents one such XBP with high binding affinity. This case-control study aimed to determine whether two common...

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Identifiers

PMID: 20499266
DOI: 10.1007/s10792-010-9374-z

Genes

GSTP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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