Article
Correlation of laterally spreading type and JC virus with methylator phenotype status in colorectal adenoma.
Human pathology - 1 May 2008
Nosho Katsuhiko, Yamamoto Hiroyuki, Takahashi Taiga, Mikami Masashi, Hizaki Keiichi, Maehata Tadateru, Taniguchi Hiroaki, Yamaoka Satoshi, Adachi Yasushi, Itoh Fumio, Imai Kohzoh, Shinomura Yasuhisa
Abstract excerpt
Accurate frequencies of CpG island methylator phenotype (CIMP) have not been determined for laterally spreading tumors (LSTs) and other flat-type colorectal adenomas, and the role of JC virus T-antigen (T-Ag) in these tumors is unclear. We used MethyLight assay to analyze the relationship between CIMP status and clinicopathologic characteristics in tissue from 72 LST of granular-type (LST-G), 35 LST of...
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