Article
RET genotypes in sporadic medullary thyroid cancer: studies in a large Italian series.
Clinical endocrinology - 1 Sept 2008
Fugazzola Laura, Muzza Marina, Mian Caterina, Cordella Daniela, Barollo Susi, Alberti Luisella, Cirello Valentina, Dazzi Davide, Girelli Maria Elisa, Opocher Giuseppe, Beck-Peccoz Paolo, Persani Luca
Abstract excerpt
BACKGROUND: Highly discrepant data about the different distribution of RET germline single nucleotide polymorphisms (SNPs) among patients with sporadic medullary thyroid cancer (sMTC) and controls are available. DESIGN AND PATIENTS: In the present case-control study, a wide panel of seven RET SNPs has been tested in the largest sMTC series and in a matched control group. RESULTS: None of the investigated...
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