Article
Association of RET genetic polymorphisms and haplotypes with papillary thyroid carcinoma in the Portuguese population: a case-control study.
PloS one - 1 Jan 2014
Santos Marina, Azevedo Teresa, Martins Teresa, Rodrigues Fernando J, Lemos Manuel C
Abstract excerpt
Thyroid cancer has a multifactorial aetiology resulting from the interaction of genetic and environmental factors. Several low penetrance susceptibility genes have been identified but their effects often vary between different populations. Somatic point mutations and translocations of the REarranged during Transfection (RET) proto-oncogene are frequently found in thyroid cancer. The aim of this case-control study...
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