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Article

Association of missense variants of the PRKC, apoptosis, WT1, regulator (PAWR) gene with schizophrenia.

Progress in neuro-psychopharmacology & biological psychiatry - 1 Apr 2008

Wang Ling-Hsuan, Chen Jen-Yeu, Liou Ying-Jay, Wang Ying-Chieh, Lai I-Ching, Liao Ding-Lieh, Chen Chia-Hsiang

Abstract excerpt

Abnormal dopamine signal transduction is implicated in the pathophysiology of schizophrenia. A recent study showed that prostate apoptosis response 4 protein (Par-4) interacts with dopamine D2 receptor and plays an important role in dopamine signaling. Par-4 knockout mice showed depression-like b...

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Source

Identifiers

PMID: 18281137
DOI: 10.1016/j.pnpbp.2008.01.003

Genes

PAWR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18281137-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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