Article
[The human dihydropyrimidinase-related protein 2 (DRP-2) gene on chromosome 8p21 is associated with paranoid-type schizophrenia].
Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology - 1 Feb 2004
Nakata Kenji, Ujike Hiroshi
Abstract excerpt
The dihydropyrimidinase-related protein (DRP) family, also called the collapsin response mediator protein, is implicated in the developmental process of the nervous system. Dysfunction of DRPs may result in neurodevelopmental abnormalities, which have been assumed to be a possible factor in the pathogenesis of schizophrenia. It has been reported that in humans, the expression of one member of the DRP family,...
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