Article
LRP8 (rs5177) and CEP85L (rs11756438) are contributed to schizophrenia susceptibility in Iranian population.
Psychiatric genetics - 1 Dec 2020
Poursaei Elham, Daneshmandpour Yousef, Aghaei Moghadam Ehsan, Abolghasemi Mahsa, Jamshidi Javad, Baradaran Behzad, Asadi Milad, Kazeminasab Somayeh, Emamalizadeh Babak
Abstract excerpt
Introduction Schizophrenia is recognized as one of the most important mental illnesses of the last century. Many genetic and environmental factors are involved in this condition. Recently, the genome-wide association study identified two significant genes LRP8 and CEP85L associated with psychiatric disorders. LRP8 (low-density lipoprotein receptor-related protein 8) acts as a cytoplasmic receptor for Reelin. Many...
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