Article
No association between prostate apoptosis response 4 gene (PAWR) in schizophrenia and mood disorders in a Japanese population.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jun 2008
Kishi Taro, Ikeda Masashi, Kitajima Tsuyoshi, Suzuki Tatsuyo, Yamanouchi Yoshio, Kinoshita Yoko, Kawashima Kunihiro, Ozaki Norio, Iwata Nakao
Abstract excerpt
Altered dopamine D2 receptor (D2R) is hypothesized to be a susceptibility factor for major psychosis. Recent studies showed that a new intracellular protein, prostate apoptosis response 4 (Par-4), plays a critical role in D2R signaling. We conducted a genetic association analysis between Par-4 gene (PAWR) and schizophrenia and mood disorders in a Japanese population (schizophrenia: 556 cases, bipolar disorder...
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