Article
Expression of luminal and basal cytokeratins in human breast carcinoma.
The Journal of pathology - 1 Jun 2004
Abd El-Rehim Dalia M, Pinder Sarah E, Paish Claire E, Bell J, Blamey R W, Robertson John F R, Nicholson Robert I, Ellis Ian O
Abstract excerpt
We have examined basal and luminal cell cytokeratin expression in 1944 cases of invasive breast carcinoma, using tissue microarray (TMA) technology, to determine the frequency of expression of each cytokeratin subtype, their relationships and prognostic relevance, if any. Expression was determined by immunocytochemistry staining using antibodies to the luminal cytokeratins (CKs) 7/8, 18 and 19 and the basal...
Topics
- Actins
- Adolescent
- Adult
- Aged
- Biomarkers, Tumor
- Breast Neoplasms
- Epithelial Cells
- Female
- Humans
- Immunohistochemistry
- Keratin-14
- Keratin-5
