Article
Basal-like phenotype is not associated with patient survival in estrogen-receptor-negative breast cancers.
Breast cancer research : BCR - 1 Jan 2007
Jumppanen Mervi, Gruvberger-Saal Sofia, Kauraniemi Päivikki, Tanner Minna, Bendahl Pär-Ola, Lundin Mikael, Krogh Morten, Kataja Pasi, Borg Ake, Fernö Mårten, Isola Jorma
Abstract excerpt
INTRODUCTION: Basal-phenotype or basal-like breast cancers are characterized by basal epithelium cytokeratin (CK5/14/17) expression, negative estrogen receptor (ER) status and distinct gene expression signature. We studied the clinical and biological features of the basal-phenotype tumors determined by immunohistochemistry (IHC) and cDNA microarrays especially within the ER-negative subgroup. METHODS: IHC was...
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