Article
Expression of basal and luminal cytokeratins in breast cancer and their correlation with clinicopathological prognostic variables.
Indian journal of medical sciences - 1 Apr 2009
Mohammadizadeh Fereshteh, Naimi Azar, Rajabi Parvin, Ghasemibasir Hamidreza, Eftekhari Amin
Abstract excerpt
BACKGROUND: Normal breast ducts contain at least 3 types of epithelial cells: luminal (glandular) cells, basal/myoepithelial cells and stem cells. Myoepithelial and luminal epithelia can be distinguished by their different cytokeratin expression patterns. The aim of this study is to evaluate the expression of some prognostic biomarkers (ER, PR and HER2), as well as histological grading and lymph node status in...
Topics
- Adult
- Biomarkers, Tumor
- Breast Neoplasms
- Carcinoma, Ductal
- ErbB Receptors
- Female
- Gene Expression
- Humans
- Keratin-5
- Keratin-6
- Keratin-7
