Article
Increased gene coverage and Alu frequency in large linkage disequilibrium blocks of the human genome.
Genetics and molecular research : GMR - 11 Dec 2007
Wang Y, Fong P Y, Leung F C C, Mak W, Sham P C
Abstract excerpt
The human genome has linkage disequilibrium (LD) blocks, within which single-nucleotide polymorphisms show strong association with each other. We examined data from the International HapMap Project to define LD blocks and to detect DNA sequence features inside of them. We used permutation tests to determine the empirical significance of the association of LD blocks with genes and Alu repeats. Very large LD blocks...
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