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Article

Genome-wide prediction of functional gene-gene interactions inferred from patterns of genetic differentiation in mice and men.

PloS one - 13 Feb 2008

Bochdanovits Zoltán, Sondervan David, Perillous Sophie, van Beijsterveldt Toos, Boomsma Dorret, Heutink Peter

Abstract excerpt

The human genome encodes a limited number of genes yet contributes to individual differences in a vast array of heritable traits. A possible explanation for the capacity our genome to generate this virtually unlimited range of phenotypic variation in complex traits is to assume functional interactions between genes. Therefore we searched two mammalian genomes to identify potential epistatic interactions by...

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Identifiers

PMID: 18270580
DOI: 10.1371/journal.pone.0001593
PMCID: PMC2217631

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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