Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human invariant Valpha24+ natural killer T cells acquire regulatory functions by interacting with IL-10-treated dendritic cells.

Blood - 15 Apr 2008

Yamaura Ayako, Hotta Chie, Nakazawa Masatoshi, Van Kaer Luc, Minami Mutsuhiko

Abstract excerpt

Glycolipid-reactive Valpha24(+) invariant natural killer T (iNKT) cells have been implicated in regulating a variety of immune responses and in the induction of immunologic tolerance. Activation of iNKT cells requires interaction with professional antigen-presenting cells, such as dendritic cells (DCs). We have investigated the capacity of distinct DC subsets to modulate iNKT cell functions. We demonstrate that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clonal Anergy
Share to Cytotoxicity, Immunologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dendritic Cells

Share to I-kappa B Proteins

Share to Interleukin-10

Share to Killer Cells, Natural

Share to Mitogen-Activated Protein Kinases

Share to T-Lymphocytes, Regulatory

Source

Identifiers

PMID: 18270329
DOI: 10.1182/blood-2007-04-085142

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human invariant Valpha24+ natural killer T cells acquire regulatory functions by interacting with IL-10-treated dendritic cells.PMID 18270329Read ↗

Distinct subsets of human invariant NKT cells differentially regulate T helper responses via dendritic cells.Semantic proximity Read ↗

Dendritic cell maturation by CD11c- T cells and Valpha24+ natural killer T-cell activation by alpha-galactosylceramide.Semantic proximity Read ↗

HLA-G expression levels influence the tolerogenic activity of human DC-10.Semantic proximity Read ↗

CD1d-restricted glycolipid antigens: presentation principles, recognition logic and functional consequences.Semantic proximity Read ↗

A gene signature of inhibitory MHC receptors identifies a BDCA3(+) subset of IL-10-induced dendritic cells with reduced allostimulatory capacity in vitro.Semantic proximity Read ↗

PD-1/PD-L blockade prevents anergy induction and enhances the anti-tumor activities of glycolipid-activated invariant NKT cells.Semantic proximity Read ↗

West Nile virus-infected human dendritic cells fail to fully activate invariant natural killer T cells.Semantic proximity Read ↗

Direct contact with natural killer cells reprograms monocyte-derived dendritic cells into a tolerogenic phenotype.Semantic proximity Read ↗

Shaping Phenotype, Function, and Survival of Dendritic Cells by Cytomegalovirus-Encoded IL-10Semantic proximity Read ↗

Identification of IDO-positive and IDO-negative human dendritic cells after activation by various proinflammatory stimuli.Semantic proximity Read ↗

Differential regulation of naïve and memory CD4+ T cells by alternatively activated dendritic cells.Semantic proximity Read ↗

IFN-γ-rich environment programs dendritic cells toward silencing of cytotoxic immune responses.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.