Article
West Nile virus-infected human dendritic cells fail to fully activate invariant natural killer T cells.
Clinical and experimental immunology - 1 Nov 2016
Kovats S, Turner S, Simmons A, Powe T, Chakravarty E, Alberola-Ila J
Abstract excerpt
West Nile virus (WNV) infection is a mosquito-borne zoonosis with increasing prevalence in the United States. WNV infection begins in the skin, and the virus replicates initially in keratinocytes and dendritic cells (DCs). In the skin and cutaneous lymph nodes, infected DCs are likely to interact with invariant natural killer T cells (iNKTs). Bidirectional interactions between DCs and iNKTs amplify the innate...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
