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Article

HLA-G expression levels influence the tolerogenic activity of human DC-10.

Haematologica - 1 Apr 2015

Amodio Giada, Comi Michela, Tomasoni Daniela, Gianolini Monica Emma, Rizzo Roberta, LeMaoult Joël, Roncarolo Maria-Grazia, Gregori Silvia

Abstract excerpt

Human leukocyte antigen (HLA)-G is a non-classical HLA class I molecule with known immune-modulatory functions. Our group identified a subset of human dendritic cells, named DC-10, that induce adaptive interleukin-10-producing T regulatory type 1 (Tr1) cells via the interleukin-10-dependent HLA-G/ILT4 pathway. In this study we aimed at defining the role of HLA-G in DC-10-mediated Tr1 cell differentiation. We...

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Identifiers

PMID: 25661445
DOI: 10.3324/haematol.2014.113803
PMCID: PMC4380729

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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