Association between the nociceptin receptor gene (OPRL1) single nucleotide polymorphisms and alcohol dependence.

doi:10.1111/j.1369-1600.2007.00089.x

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Article

Association between the nociceptin receptor gene (OPRL1) single nucleotide polymorphisms and alcohol dependence.

Addiction biology - 1 Mar 2008

Huang Jia, Young Brandon, Pletcher Mathew T, Heilig Markus, Wahlestedt Claes

Abstract excerpt

OPRL1 encodes the nociceptin receptor, which has been shown to be involved in alcohol dependence in previous studies. In the present study, we investigated the association between genetic polymorphisms of OPRL1 and alcohol dependence in a Scandinavian population. We genotyped 15 single nucleotide polymorphisms (SNPs) spanning the OPRL1 locus and found that SNP rs6010718 was significantly associated with both Type...

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PMID: 18269382
DOI: 10.1111/j.1369-1600.2007.00089.x

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OPRL1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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