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Article

Endogenous opioid receptor genes and alcohol dependence among Taiwanese Han.

Alcoholism, clinical and experimental research - 1 Jan 2004

Loh El Wui, Fann Cathy S J, Chang Yuh Terng, Chang Ching Jui, Cheng Andrew T A

Abstract excerpt

BACKGROUND: Nonselective opioid antagonists reduce alcohol consumption under various experimental situations, and several association studies have examined possible roles of opioid receptor mu (OPRM), delta (OPRD), and kappa (OPRK) genes in the development of alcohol dependence. METHODS: We examined 20 single nucleotide polymorphisms (SNPs) across the OPRM, OPRD, and OPRK genes in 158 alcohol-dependent subjects...

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Identifiers

PMID: 14745298
DOI: 10.1097/01.ALC.0000106303.41755.B8

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