[OPRD1 gene polymorphism (rs4654327) as a potential predictor of the effectiveness of long-acting naltrexone in patients with alcohol addiction].

doi:10.17116/jnevro202612604156

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[OPRD1 gene polymorphism (rs4654327) as a potential predictor of the effectiveness of long-acting naltrexone in patients with alcohol addiction].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 2026

Miroshkin S S, Skryabin V Y, Shipitsyn V V, Masyakin A V

Abstract excerpt

OBJECTIVE: To evaluate the effect of the A>G (rs4654327) polymorphism of the OPRD1 gene on the clinical efficacy of long-acting naltrexone therapy in patients with alcohol addiction. MATERIAL AND METHODS: The study included 100 patients with alcohol addiction treated with long-acting naltrexone for 180 days. The duration of remission, the recurrence rate, the completion of the treatment course, the change of...

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PMID: 42133415
DOI: 10.17116/jnevro202612604156

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OPRD1

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