Article
The origin of asymmetry: early polarisation of the Drosophila germline cyst and oocyte.
Current biology : CB - 8 Jun 2004
Huynh Jean-René, St Johnston Daniel
Abstract excerpt
The anterior-posterior axis of Drosophila is established before fertilisation when the oocyte becomes polarised to direct the localisation of bicoid and oskar mRNAs to opposite poles of the egg. Here we review recent results that reveal that the oocyte acquires polarity much earlier than previously thought, at the time when it acquires its fate. The oocyte arises from a 16-cell germline cyst, and its selection...
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