Article
Regulation of somatic myosin activity by protein phosphatase 1β controls Drosophila oocyte polarization.
Development (Cambridge, England) - 1 May 2011
Sun Yi, Yan Yan, Denef Natalie, Schüpbach Trudi
Abstract excerpt
The Drosophila body axes are established in the oocyte during oogenesis. Oocyte polarization is initiated by Gurken, which signals from the germline through the epidermal growth factor receptor (Egfr) to the posterior follicle cells (PFCs). In response the PFCs generate an unidentified polarizing signal that regulates oocyte polarity. We have identified a loss-of-function mutation of flapwing, which encodes the...
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