Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Drosophila RGS protein Loco is required for dorsal/ventral axis formation of the egg and embryo, and nurse cell dumping.

Mechanisms of development - 1 Dec 2001

Pathirana S, Zhao D, Bownes M

Abstract excerpt

The loco gene encodes members of a family of RGS proteins responsible for the negative regulation of G-protein signalling. At least two transcripts of loco are expressed in oogenesis, loco-c2 is observed in the anterior-dorsal follicle cells and is downstream of the epidermal growth factor receptor signalling pathway, initiated in the oocyte. loco-c3 is a new transcript of loco, which is expressed in the nurse...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Insect Proteins
Share to Oligonucleotides, Antisense
Share to Oogenesis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to RGS Proteins

Share to Tissue Distribution

Share to Transforming Growth Factor alpha

Share to Transforming Growth Factors

Source

Identifiers

PMID: 11731228
DOI: 10.1016/s0925-4773(01)00557-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Drosophila RGS protein Loco is required for dorsal/ventral axis formation of the egg and embryo, and nurse cell dumping.PMID 11731228Read ↗

The RGS gene loco is essential for male reproductive system differentiation in Drosophila melanogaster.Semantic proximity Read ↗

loco encodes an RGS protein required for Drosophila glial differentiation.Semantic proximity Read ↗

The receptor-like tyrosine phosphatase lar is required for epithelial planar polarity and for axis determination within drosophila ovarian follicles.Semantic proximity Read ↗

The ovo gene of Drosophila encodes a zinc finger protein required for female germ line development.Semantic proximity Read ↗

Lethal(2)giant larvae is required in the follicle cells for formation of the initial AP asymmetry and the oocyte polarity during Drosophila oogenesis.Semantic proximity Read ↗

maelstrom is required for an early step in the establishment of Drosophila oocyte polarity: posterior localization of grk mRNA.Semantic proximity Read ↗

The Hippo pathway controls polar cell fate through Notch signaling during Drosophila oogenesis.Semantic proximity Read ↗

The identification of novel genes required for Drosophila anteroposterior axis formation in a germline clone screen using GFP-Staufen.Semantic proximity Read ↗

spoonbill, a new Drosophila female-sterile mutation, interferes with chromosome organization and dorsal-ventral patterning of the egg.Semantic proximity Read ↗

mago nashi mediates the posterior follicle cell-to-oocyte signal to organize axis formation in Drosophila.Semantic proximity Read ↗

Juno is the egg Izumo receptor and is essential for mammalian fertilizationSemantic proximity Read ↗

Lgd regulates the activity of the BMP/Dpp signalling pathway during Drosophila oogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.