Article
Frequent unanticipated alleles of lethal giant larvae in Drosophila second chromosome stocks.
Genetics - 1 May 2009
Roegiers Fabrice, Kavaler Joshua, Tolwinski Nicholas, Chou Yu-Ting, Duan Hong, Bejarano Fernando, Zitserman Diana, Lai Eric C
Abstract excerpt
Forty years ago, a high frequency of lethal giant larvae (lgl) alleles in wild populations of Drosophila melanogaster was reported. This locus has been intensively studied for its roles in epithelial polarity, asymmetric neural divisions, and restriction of tissue proliferation. Here, we identify a high frequency of lgl alleles in the Bloomington second chromosome deficiency kit and the University of California...
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