Potassium channel phosphorylation in excitable cells: providing dynamic functional variability to a diverse family of ion channels.

Abstract excerpt

Phosphorylation of potassium channels affects their function and plays a major role in regulating cell physiology. Here, we review previous studies of potassium channel phosphorylation, focusing first on studies employing site-directed mutagenesis of recombinant channels expressed in heterologous cells. We then discuss recent mass spectrometric-based approaches to identify and quantify phosphorylation at specific...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Ion Channel Gating
• Share to Mass Spectrometry