Article
Alcohol and aldehyde dehydrogenase polymorphisms in Chinese and Indian populations.
Substance use & misuse - 1 Jan 2010
Tan Ene-Choo, Lim Leslie, Leong Jern-Yi, Lim Jing-Yan, Lee Arthur, Yang Jun, Tan Chay-Hoon, Winslow Munidasa
Abstract excerpt
The association between two functional polymorphisms in alcohol dehydrogenase (ADH2/ADH1B) and aldehyde dehydrogenase (ALDH2) genes and alcohol dependence was examined in 182 Chinese and Indian patients undergoing treatment for alcohol dependence and 184 screened control subjects from Singapore. All subjects were screened by the Alcohol Use Disorders Identification Test (AUDIT). Patients were also administered...
Topics
- Adult
- Aged
- Alcohol Dehydrogenase
- Alcoholism
- Aldehyde Dehydrogenase
- Aldehyde Dehydrogenase, Mitochondrial
- Alleles
- Asian People
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- India
- Male
- Middle Aged