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Article

A vitamin K epoxide reductase complex subunit 1 mutation in an Irish patient with warfarin resistance.

Irish journal of medical science - 1 Jun 2008

Ainle F N, Mumford A, Tallon E, McCarthy D, Murphy K

Abstract excerpt

BACKGROUND: Oral anticoagulant use continues to increase rapidly. In this setting, it is important to recognise that some normal individuals can demonstrate resistance to anticoagulation with warfarin. Such patients require high daily doses of warfarin (>20 mg) in order to maintain an international normalised ratio (INR) within the target therapeutic range (2-3). We describe the case of an elderly gentleman with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18266023
DOI: 10.1007/s11845-008-0126-2

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A vitamin K epoxide reductase complex subunit 1 mutation in an Irish patient with warfarin resistance.PMID 18266023Read ↗

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