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Erythroblast Enucleation

1 Jan 2011

Abstract excerpt

Even though the production of orthochromatic erythroblasts can be scaled up to fulfill clinical requirements, enucleation remains one of the critical rate-limiting steps in the production of transfusable red blood cells. Mammalian erythrocytes extrude their nucleus prior to entering circulation, likely to impart flexibility and improve the ability to traverse through capillaries that are half the size of...

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Identifiers

PMID: 22007239
DOI: 10.4061/2011/139851

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