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Article

Molecular signature of erythroblast enucleation in human embryonic stem cells

7 Apr 2015

Abstract excerpt

While enucleation is a critical step in the terminal differentiation of human red blood cells, the molecular mechanisms underlying this unique process remain unclear. To investigate erythroblast enucleation, we studied the erythroid differentiation of human embryonic stem cells (hESCs), which provide a unique model for deeper understanding of the development and differentiation of multiple cell types. First,...

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PMID: 25850942
DOI: 10.1002/stem.2027

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