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Enucleation of human erythroblasts involves non-muscle myosin IIB

3 Nov 2011

Abstract excerpt

Mammalian erythroblasts undergo enucleation, a process thought to be similar to cytokinesis. Although an assemblage of actin, non-muscle myosin II, and several other proteins is crucial for proper cytokinesis, the role of non-muscle myosin II in enucleation remains unclear. In this study, we investigated the effect of various cell-division inhibitors on cytokinesis and enucleation. For this purpose, we used human...

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Identifiers

PMID: 22049517
DOI: 10.1182/blood-2011-06-361907

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