Cdc42 regulates cell polarization and contractile actomyosin rings during terminal differentiation of human erythroblasts

Abstract excerpt

The molecular mechanisms involved in the terminal differentiation of erythroblasts have been elucidated by comparing enucleation and cell division. Although various similarities and differences between erythroblast enucleation and cytokinesis have been reported, the mechanisms that control enucleation remain unclear. We previously reported that dynein and microtubule-organizing centers mediated the polarization...

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