Article
A novel isoform of Tensin1 promotes actin filament assembly for efficient erythroblast enucleation
2024-12-17
Abstract excerpt
Mammalian red blood cells are generated via a terminal erythroid differentiation pathway culminating in cell polarization and enucleation. Actin filament polymerization is critical for enucleation, but the molecular regulatory mechanisms remain poorly understood. We utilized publicly available RNA-seq and proteomics datasets to mine for actin-binding proteins and actin- nucleation factors differentially expressed...
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Identifiers and source
- Literature Corpus work
- 37bb85a7-7e3d-5983-b4ab-2999dac75cb4
- DOI
- 10.1101/2024.12.13.628322