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Article

Influence of MDM2 SNP309 alone or in combination with the TP53 R72P polymorphism in oligodendroglial tumors.

Brain research - 10 Mar 2008

Idbaih Ahmed, Boisselier Blandine, Marie Yannick, Sanson Marc, El Hallani Soufiane, Crinière Emmanuelle, Fourtassi Maryam, Paris Sophie, Carpentier Catherine, Rousseau Audrey, Mokhtari Karima, Combadière Christophe, Laigle-Donadey Florence, Hoang-Xuan Khê, Delattre Jean-Yves

Abstract excerpt

The transcription factor p53 and its negative regulator MDM2 are pivotal in normal and cancer cells biology. Recently, a functional single-nucleotide polymorphism in the promoter region of MDM2 (MDM2 SNP309), alone or in combination with TP53 R72P, was shown to be associated with the risk, prognosis, age at onset, molecular markers, and response to chemotherapy of various cancers. This SNP has never been...

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Source

Identifiers

PMID: 18262501
DOI: 10.1016/j.brainres.2008.01.027

Genes

MDM2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Influence of MDM2 SNP309 alone or in combination with the TP53 R72P polymorphism in oligodendroglial tumors.PMID 18262501Read ↗

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