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Article

Pharmacological analyses of two naturally occurring porcine melanocortin-4 receptor mutations in domestic pigs.

Domestic animal endocrinology - 1 May 2008

Fan Zhen-Chuan, Sartin James L, Tao Ya-Xiong

Abstract excerpt

The melanocortin-4 receptor (MC4R) is critical in regulating mammalian food intake and energy expenditure. Numerous mutations in the MC4R gene have been identified from obese humans. So far two naturally occurring porcine MC4R (pMC4R) mutations, D298N and R236H, have been identified from various strains of pigs and D298N is being utilized as a genetic marker to screen performance traits of pigs. In this study, we...

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PMID: 18262384
DOI: 10.1016/j.domaniend.2007.05.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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