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Article

Pharmacological characterization of canine melancortin-4 receptor and its natural variant V213F.

Domestic animal endocrinology - 1 Aug 2011

Yan J, Tao Y-X

Abstract excerpt

Dogs have become one of the most important companion animals in modern society. However, it is estimated that 20% to 40% of owned dogs are obese, suggesting that obesity has become one of the most important canine health problem. In addition, obesity in dogs also leads to type II diabetes. Because the melanocortin-4 receptor (MC4R) has been shown to be essential in maintaining energy homeostasis in several...

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Identifiers

PMID: 21741577
DOI: 10.1016/j.domaniend.2011.05.002
PMCID: PMC3155386

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