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Article

Limbic and frontal cortical degeneration is associated with psychiatric symptoms in PINK1 mutation carriers.

Biological psychiatry - 1 Aug 2008

Reetz Kathrin, Lencer Rebekka, Steinlechner Susanne, Gaser Christian, Hagenah Johann, Büchel Christian, Petersen Dirk, Kock Norman, Djarmati Ana, Siebner Hartwig R, Klein Christine, Binkofski Ferdinand

Abstract excerpt

BACKGROUND: Mutations in the PINK1 gene can cause Parkinson's disease and are frequently associated with psychiatric symptoms that might even precede motor signs. METHODS: To determine whether specific gray matter degeneration of limbic and frontal structures might be liable to different psychiatric symptoms in PINK1 mutation carriers, observer-independent voxel-based morphometry was applied to high-resolution...

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Source

Identifiers

PMID: 18261714
DOI: 10.1016/j.biopsych.2007.12.010

Genes

PINK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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