Article

Cerebellar and subcortical atrophy contribute to psychiatric symptoms in frontotemporal dementia

2021-11-16

Abstract excerpt

Recent studies have suggested that cerebellar and subcortical structures are impacted early in the disease progression of genetic frontotemporal dementia (FTD) due to microtubule-associated protein tau ( MAPT ), progranulin ( GRN ) and chromosome 9 open reading frame 72 ( C9orf72 ). However, the clinical contribution of the structures involved in the cerebello-subcortical circuitry has been understudied in FTD...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6d1f1d38-40b6-5574-8ae8-6773e1a04898
DOI: 10.1101/2021.11.12.468429

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Cerebellar and subcortical atrophy contribute to psychiatric symptoms in frontotemporal dementiaDOI 10.1101/2021.11.12.468429Read

Patterns of regional cerebellar atrophy in genetic frontotemporal dementia.Semantic proximity Read

Differential early subcortical involvement in genetic FTD within the GENFI cohort.Semantic proximity Read

Anatomical progression of genetic frontotemporal lobar degeneration across the lifespanSemantic proximity Read

Thalamic pathology in frontotemporal dementia: Predilection for specific nuclei, phenotype-specific signatures, clinical correlates, and practical relevance.Semantic proximity Read

Patterns of gray matter atrophy in genetic frontotemporal dementia: results from the GENFI study.Semantic proximity Read

Neuroimaging signatures of frontotemporal dementia genetics: C9ORF72, tau, progranulin and sporadics.Semantic proximity Read

Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis.Semantic proximity Read

Neurodevelopmental effects of genetic frontotemporal dementia mutations revealed by total intracranial volume differencesSemantic proximity Read

Infratentorial pathology in frontotemporal dementia: cerebellar grey and white matter alterations in FTD phenotypes.Semantic proximity Read

Presymptomatic grey matter alterations in ALS kindreds: a computational neuroimaging study of asymptomatic C9orf72 and SOD1 mutation carriers.Semantic proximity Read

Distinct Subtypes of Behavioral Variant Frontotemporal Dementia Based on Patterns of Network Degeneration.Semantic proximity Read

Mapping behavioural, cognitive and affective transdiagnostic dimensions in frontotemporal dementiaSemantic proximity Read